At least two people were killed Friday after a small airplane crashed onto a busy road and collided with a bus in São Paulo, southern Brazil, injuring several others. The crash took place around 7:20 a.m. local time (5:20 a.m. ET) along Avenida Marquês in the coastal district of Barra Funda, CNN affiliate CNN Brasil reported.

Brazil has had a number of deadly aircraft crashes in recent years, including one last August in Vinhedo, near Sao Paulo, that was particularly shocking. That passenger plane fell in a flat spin before crashing into the back yard of a home in a gated community, killing all those on board.