The San Francisco 49ers officially have a significant injury problem on their hands. Running back Christian McCaffrey is out for at least three more weeks while he tends to his Achilles tendinitis. His absence already made things more difficult for the 49ers' offense.

By the looks of their respective injury reports, the Los Angeles Rams and San Francisco 49ers are sending out their B teams in Week 3.

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 49ers vs. Rams game.

The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle reported soreness in his hamstring after Wednesday's practice. Kittle sat out practice Thursday,

Pregame analysis and predictions of the San Francisco 49ers vs. Los Angeles Rams NFL game to be played on September 22, 2024 on ESPN.

The Rams have their work cut out for them in Week 3 but they have a chance to upset the 49ers if they win these 5 matchups

After their offense went stagnant in Week 2 without one of their star performers, the San Francisco 49ers will look to recover Sunday when they visit their home away from