Meet some of the wildest animal hybrids. Which occur naturally, which are found only in zoos, and which come straight out of the science lab?

From zebra-striped donkeys to massive feline hybrids, these human-made creatures challenge nature’s rules. Discover 11 unusual and rare crossbreeds you may have never heard of before.

(Learn more about ligers and other big cat hybrids.) Also, the parent species may sport incompatible genetic differences, such as different numbers of chromosomes.

(Learn more about ligers and other big cat hybrids.) Also, the parent species may sport incompatible genetic differences, such as different numbers of chromosomes.

Bird flu has taken a terrible toll at the Wild Felid Advocacy Center, a sanctuary for wildcats and their hybrids on Harstine Island, killing 20 cats — half the animals in its care.