Single-cell RNA sequencing has transformed biology by showing which genes are active in individual cells. However, this approach requires cells to be removed from their natural environment, erasing ...

New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...

Hydrogel micromachines recreate the push and pull of living cells, helping scientists study how mechanical forces shape tissues in the lab.

For decades, lab-grown cells have been studied in materials that don't reflect the softness and flexibility of human tissue.

Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...

In developing hearts, cells shuffle around, bumping into each other to find their place, and the stakes are high: pairing with the wrong cell could mean the difference between a beating heart and one ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...