Connective tissue cells are capable of both synthesizing and degrading the macromolecular components of the extracellular matrix. The degradation of proteoglycan and collagen has been shown to be ...

The Journal of Biophysical and Biochemical Cytology, Vol. 6, No. 2 (Oct., 1959), pp. 207-214 (8 pages) After incubation of pigeon pancreas slices with P32 and isolation of various fractions by ...

New research revealed contrasting roles for the SNAP23 protein in pancreatic secretion of digestive enzymes and hormones such as insulin. Inhibiting SNAP23 with a potential new diabetes drug enabled ...

A new study has uncovered a critical role for the enzyme Glucose-6-phosphatase 2 (G6PC2) in regulating blood sugar levels. The research sheds new light on how this enzyme influences glucagon secretion ...

Immunostaining of G6PC2 in human pancreatic alpha cells showing G6PC2 in red, alpha cells in green and beta cells in blue. New study shows that the gene G6PC2 plays an important role in regulating ...

With the help of the CRISPR/Cas9 gene scissors, researchers have managed to “turn off” an enzyme that proved to play a key role in the regulation of the diabetes-associated TXNIP gene. The results are ...

Exocrine pancreatic insufficiency (EPI) is characterized by a deficiency of exocrine pancreatic enzymes, resulting in deficits in digestion of all macronutrients, with deficiencies in digestion of ...

Research reveals opposing roles for SNAP23 protein in the enzyme- and hormone-secretion functions of the pancreas; SNAP23 inhibitor increased insulin secretion in mice, suggesting potential use as a ...