Nature

Indirect, but not direct, lateral habenula projections to ventral tegmental area regulate the long-term consequences of neuropathic pain

Chronic pain, in which pain persists or recurs for more than 3 months, is a major cause of suffering and disability worldwide. Chronic pain caused by an insult to the somatosensory nervous system is ...
Nature

Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area

Chronic neuropathic pain is an increasing public health concern. The International Association for the Study of Pain (IASP) defines neuropathic pain as “pain caused by a lesion or disease of the ...