Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

This disruption has wide-ranging effects. When SIRT1 is suppressed, the liver shifts toward storing fat instead of burning it ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats. These molecules undergo further modification in ...

A medicine that has been used for decades to treat asthma may one day help people with a serious liver disease that affects ...

Researchers evaluated whether restoring the gut microbiome to a youthful state in mice could hold the key to slowing aging and preventing liver cancer, one of the fastest-growing cancers worldwide.

If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first ...