MastCURe, a high-profile research consortium, has been awarded €1.3M in funding from the Eureka Eurostars program. The ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

What Is Advanced Systemic Mastocytosis? Mast cells, found in connective tissue throughout the body, are a type of white blood cell that helps the immune system function properly and protect against ...

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause ...

Scientists show that prenatal stress reshapes fetal mast cells and sensory neurons, creating a fragile skin barrier that sparks early-life eczema in mice. Study: Maternal stress triggers early-life ...

Jeanetta has been feeling poorly and never knew why until recently. Now 75, she's suffered for years with intermittent headaches, muscle and joint pain, fatigue and sometimes even broke out in rashes ...

Three G protein–coupled receptors, the cysteinyl leukotriene receptors 1, 2, and 3 (CysLTR1, CysLTR2, and CysLTR3), mediate the effects of the cysteinyl leukotrienes in vivo. (Each receptor has a ...

Systemic mastocytosis (SM) is a rare blood disorder in which the body produces too many mast cells. Part of the immune response, mast cells are a type of white blood cell that releases histamine in ...