What is the benefit of the determination of quantitative PCR for polyomavirus in renal transplant recipients? And is there any value in screening kidney donors for polyomavirus? The need for giving ...

A benign virus normally found in the skin can lead to a type of rare, lethal skin cancer. Specifically, infection by the Merkel cell polyomavirus can lead to Merkel cell carcinoma in ...

While uncommon, BK polyomavirus-associated nephropathy is associated with a "substantial" risk of graft loss in kidney transplant recipients. BK polyomavirus-associated nephropathy may increase the ...

It has recently been shown that Merkel cell carcinoma, a rare and often lethal cutaneous malignancy, frequently harbors a novel clonally integrated polyomavirus aptly named Merkel cell polyomavirus.

From July 2001 to April 2004, we used leflunomide as the initial antiviral therapy in 17 patients with biopsy-proven BK nephropathy. All but one of these patients was receiving tacrolimus, prednisone, ...

Nephropathy associated with the polyomavirus type BK (BKV) nephropathy has emerged as a cause of allograft failure linked to immunosuppressive regimens containing tacrolimus or mycophenolate mofetil.

Background: A 36-year-old white female, who had received a deceased-donor kidney transplant for end-stage renal disease secondary to reflux nephropathy 8 years previously, was referred to a transplant ...

The BK polyomavirus exhibits tropism for the renal tubular epithelium, where it establishes latent infection. Vigorous immunosuppression of renal allograft recipients can lead to reactivation of the ...

ANN ARBOR, Mich. -- Every cell in our body runs like a tiny factory that makes specialized products, using the carefully guarded instructions kept in the CEO's office. But every once in a while, an ...

If every cell in our body is a factory, viruses are industrial spies who try to break in and take over. New findings about how one of the most mysterious types of spy - polyomaviruses -- accomplishes ...

Every cell in our body runs like a tiny factory that makes specialized products, using the carefully guarded instructions kept in the CEO's office. But every once in a while, an invader tries to get ...