News Medical

In silico docking of clinically approved drugs against the SARS-CoV-2 receptor-binding domain

In this study in silico docking models were employed to investigate the molecular interactions between the receptor-binding domain (RBD) of the SARS-CoV-2 spike glycoprotein, derived from the ...
News Medical

Bacteria repurpose viral injection systems to target diverse cells

New study shows how bacteria adapted a virus-derived injection system to recognize and attach to many different types of cells. By systematically identifying thousands of rapidly evolving ...
C&EN

2-in-1 mass spec method speeds up drug discovery

An illustration of an antibody disrupting the binding between a virus particle and a receptor on the edge of a membrane. A drug (orange) blocks the SARS-CoV-2 virus (gold sphere with white protruding ...
Phys.org

How bacteria learned to target numerous cell types

Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and bind to receptors on the surface of target cells, a molecular arms race that ...
Miami University

B48 - Investigating Animal Rotavirus Receptor Binding Domains Interactions with Human Receptors to Understand Zoonotic Potential

Mentor(s): Michael Kennedy, Ph.D. Understanding binding of animal rotavirus strains offers insight into zoonotic potential The goal of this project is to determine if bat P[10] binds in an excited ...