Sex differences in physiological and disease traits are pervasive and begin during early development, but the genetic architecture of these differences is largely unknown. Here, we leverage the human ...

Gene expression is orchestrated by a complex network of regulatory machinery, including but not limited to transcription factors (TFs), enhancers, repressors and three-dimensional chromosomal ...

De novo genes are evolution’s magic trick—new genes appearing from non-coding DNA, much like a rabbit pulled from a hat. Once considered impossible, de novo genes have been identified in Drosophila ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

For millennia, evolution has intrigued many great thinkers, prompting questions about how new traits emerge as species adapt over time. Then, attention shifted to natural selection and the inheritance ...

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. Alternative splicing—the way cells edit gene messages—forms a second, independent layer of ...

An international study using artificial intelligence has shown that our personalities alter the expression of our genes. The findings shed new light on the long-standing mystery of how the mind and ...

The findings converge on pathways involved in glutamate signaling, neuronal communication, immune processes, and neurodevelopment.