Defragmentation has certainly solved a lot of problems. Many years ago file fragmentation–the splitting of files into multiple pieces so as to make more of disk space–was found to be the cause of many ...
In the Dark Ages of computing, defragmenting a hard disk was something you had to do regularly to keep it running at peak efficiency. Those defragmenter utilities typically included visualizations, ...
So make sure you disable prefetchers. Also, especially with Vista and windows 7, make sure you disable defragmentation on the SSD disk. You do not have a mechanical drive anymore so it is not needed, ...