The Carolina Panthers face the San Francisco 49ers on Monday, Nov. 24, 2025 at Levi’s Stadium in Santa Clara, California.

The Carolina Panthers and the San Francisco 49ers take the field for NFL Monday Night Football tonight in Week 12. MNF start time, schedule and how to watch.

At 6-5 with a playoff berth within reach, the Carolina Panthers roll into primetime carrying equal parts urgency and belief. Across the field, the 7-4 San Francisco 49ers enter Monday night trying to steady themselves after an uneven stretch,

Broadcast and streaming information for the San Francisco 49ers Week 11 matchup against the Arizona Cardinals at State Farm Stadium.

Follow along with live updates as the San Francisco 49ers and Carolina Panthers put their playoff hopes on the line in Week 12.

Christian McCaffrey galloped for 142 yards and the San Francisco 49ers defense allowed just 230 to power a primetime win over the Carolina Panthers.

The San Francisco 49ers are hosting the Carolina Panthers In the Week 12 edition of "Monday Night Football'' with San Francisco coming off a blowout victory over the division rival Arizona Cardinals,

Christian McCaffrey was a steady force as the San Francisco 49ers won a sloppy "Monday Night Football" game against the Carolina Panthers.