In proteomics applications of tandem mass spectrometry (MS/MS), one of the core analysis challenges is the de novo sequencing problem: given an observed fragmentation spectrum, can we infer the amino ...
We spoke to David Klenerman, co-developer of sequencing by synthesis, to find out how his work heralded the next generation ...
Elucidating antibody sequences by mass spectrometry-based de novo sequencing is essential but remains technically challenging. Here we present XA-Novo, an accurate and high-throughput de novo ...
In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...
A new study shows that long-read sequencing has the potential to improve the rate of diagnosis while reducing the time to diagnosis from years to days -- in a single test and at a much lower cost. One ...
A few years ago, a new NGS platform being announced at the Advances in Genome Biology and Technology (AGBT) meeting would not have been a surprise; multiple new instruments entered the NGS arena over ...
Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...
When it comes to finding answers, every moment counts—especially in critical care settings like the neonatal and pediatric intensive care units (NICU and PICU). Although rapid genetic tests, whether ...
One in every 10 people worldwide is impacted by a rare genetic disease but about 50% of them remain undiagnosed despite rapid increases in genetic technology and testing. Even when a person does have ...
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