Dupuytren’s contracture is a condition that causes the tissue under the skin of the palm to thicken, pulling fingers inward. Its progression rate varies among individuals. While there is no definitive ...

Treatments for Dupuytren’s contracture include limited fasciectomy and collagenase injection. Comparisons of the effectiveness of these treatments have been limited. We performed an unblinded, ...

For some people, the condition may only cause lumps in the palm and never worsen, while others may develop severely bent fingers that cannot be fully straightened. If the lumps or contractures aren't ...

Xiaflex was approved in 2010 for the treatment of Dupuytren’s contracture. Dupuytren’s contracture is a condition where nodules form under the skin in the palm of the hand. These nodules thicken and ...

If you have Dupuytren's contracture, you're likely familiar with the many nonsurgical ways to manage the condition, including hand exercises, physical therapy, and injections. While these treatments ...