Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by protean clinical manifestations that are associated with immune system dysregulation. Of these manifestations, pain ...

Systemic sclerosis (SSc) is a prototypical systemic immune-mediated fibrosing disease that affects the skin, the lungs, the heart, the kidneys and the intestinal tract. Similar to many other fibrotic ...

University of Pittsburgh postdoctoral researcher Mary Cundiff uses machine learning and single-cell genomics to study ...

The term scleritis describes a chronic inflammation that involves the outermost coat and skeleton of the eye. Disease can be isolated to the eye, but in up to half of affected individuals it occurs in ...

Researchers have identified three distinct subgroups of Sjögren syndrome (SS) with different prognoses. While previous efforts to stratify these patients were based on reported symptoms, this new ...

What Is Advanced Systemic Mastocytosis? Mast cells, found in connective tissue throughout the body, are a type of white blood cell that helps the immune system function properly and protect against ...

Ophthalmologists can detect alterations such as hypertension, diabetes, cardiac and hepatic pathology, and even tumors through clues in different parts of the ocular organs. The eye, an organ exposed ...

The eye is a unique window to overall health. Its associated medical imaging has great characteristics, such as being non-invasive, convenient, and rich in information, which offers significant ...

This activity was supported by a contract between the National Academy of Sciences and the Administration for Strategic Preparedness and Response (75A50121C00061). Any opinions, findings, conclusions, ...

There is a complex pathological relationship between diabetes and osteoporosis, two of the most common chronic diseases worldwide.

Systemic mastocytosis (SM) is a rare blood disorder in which the body produces too many mast cells. Part of the immune response, mast cells are a type of white blood cell that releases histamine in ...