There were plenty of funny pair ups on 'The Big Bang Theory,' But here are five moments that prove Sheldon and Penny were the show's cutest duo.

Despite Penny’s career arc taking center stage in The Big Bang Theory season 7, it was never really the focus in and of ...

However, Penny gives him something irreplaceable: an autograph of Leonard Nimoy. "The Bath Item Gift Hypothesis" is among the best Sheldon episodes in The Big Bang Theory.

Sheldon Cooper and Penny didn't seem to have much in common, but the 'The Big Bang Theory' besties might have the been the best friend pairing on the show.

Well, the nerd wedding of the century is almost upon us on The Big Bang Theory and the latest episode saw Amy finding the perfect dress for her marriage to Sheldon in the most heartwarming way.

From Raj and Penny to Leonard and Sheldon, we ranked the best duos from the iconic sitcom, The Big Bang Theory.

One The Big Bang Theory actor's near-miss with a legendary sitcom role took place at a fateful audition that almost changed ...