The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...
DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.
In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...
The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...
A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...
Understanding human gene function in living organisms has long been hampered by fundamental differences between species.
Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.