Abstract. Lung cancer is the leading cause of cancer death worldwide, with non-small cell lung cancer (NSCLC) accounting for approximately 85% of all lung cancers. At the time of diagnosis, it is ...
Abstract. Monomethyl auristatin E (MMAE), the payload delivered by vedotin ADCs, exerts its cytotoxic effects via microtubule disruption and induction of ER stress, leading to apoptosis and tumor cell ...
Cancer Res (2023) 83 (7_Supplement): ND02.
Abstract. Despite demonstrated efficiency in antibody generation, classical immunization strategies and subsequent hybridoma generation often face strong limitations when it comes to complex targets ...
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1Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV), Lausanne, Switzerland. 2Centre for Haematology, Department of Immunology and Inflammation, Imperial ...
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Cancer Res (2023) 83 (8_Supplement): LB031.