Researchers devised a reversibly lockable DNA device for enclosing an enzyme and controlling its access to substrates. Turning on and off the activity of a single enzyme on demand is a much desired ...

Enzymes are biological catalysts. In simple terms, they speed up chemical reactions. Living organisms have chemical reactions ...

Investigators at St. Jude Children's Research Hospital have discovered a new way that an enzyme crucial to the cell's ability to decode genes and duplicate chromosomes can be turned into a poison ...

A pharmaceutical scientist at the National University of Singapore (NUS) has developed a method that can measure the kinetic efficiency of an enzyme against more than 200,000 potential peptide ...

In synthetic biology, the control of gene expression requires a multistep processing of biological signals. The key steps are sensing the environment, computing information and outputting products. To ...

A new type of assay based on click chemistry will make it possible to carry out high-throughput screens to find inhibitors of the gut hormone ghrelin, a target for obesity and diabetes medications.

New research identifies several existing compounds that block replication of the COVID-19 virus (SARS-CoV-2) within human cells grown in the laboratory. The inhibitors all demonstrated potent chemical ...

NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development Researchers at the National Institutes of Health have discovered that a rare tumor of the adrenal glands appears to ...

This is a preview. Log in through your library . Abstract The fluorogenic model substrates, methylumbelliferyl [MUF]-β-D-glucoside, MUF-phosphate and MUF-sulphate, were used to investigate the ...