Abstract. Monomethyl auristatin E (MMAE), the payload delivered by vedotin ADCs, exerts its cytotoxic effects via microtubule disruption and induction of ER stress, leading to apoptosis and tumor cell ...
Cancer Res (2023) 83 (7_Supplement): ND02.
Cancer Res (2022) 82 (22_Supplement): A019.
Abstract. Despite demonstrated efficiency in antibody generation, classical immunization strategies and subsequent hybridoma generation often face strong limitations when it comes to complex targets ...
ARV-471 is a selective, orally bioavailable PROteolysis-TArgeting Chimera (PROTAC®) small molecule that induces wild-type and mutant estrogen receptor (ER) alpha degradation via the ...
To help defray the rising costs of initial manuscript screening and publication, the AACR journals levy fees as detailed herein. Authors are required to confirm at the time of submission that they ...
1Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Cancer Res (2019) 79 (13_Supplement): 3278.
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For authors of Research Articles that have been declined for publication at an AACR journal, the AACR offers the corresponding author the option to easily transfer manuscript files and supporting ...
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