More than 8 decades have passed since Wartman first proposed the causative role of intraplaque hemorrhage (IPH) in the progression of coronary artery lesions, 1 yet the intricate mechanisms by which ...
Hypertension‐induced cardiovascular remodeling is characterized by chronic low‐grade inflammation. Interleukin‐4 receptor α (IL‐4Rα) signaling is importantly involved in cardiovascular remodeling, ...
© 2025 The Authors.Circulation Research is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article ...
New therapeutic approaches are required for secondary prevention of residual vascular risk after stroke. Diverse sources of evidence support a causal role for inflammation in the pathogenesis of ...
Division of Cardiovascular Medicine (R.J., C.M.T.), UMass Chan Medical School; Worcester. Department of Medicine (R.J., C.M.T.), UMass Chan Medical School; Worcester ...
Women are known to be disadvantaged compared with men in the early links of the Chain of Survival, receiving fewer bystander interventions. We aimed to describe sex‐based disparities in emergency ...
Objective— Regulatory T (Treg) cells play a protective role in experimental atherosclerosis. In the present study, we investigated whether the levels of circulating Treg cells relate to the degree of ...
Stroke is a leading cause of death worldwide, with a lack of effective treatments for improving the prognosis. The aim of the present study was to identify novel therapeutic targets for functional ...
STAIR XII (12th Stroke Treatment Academy Industry Roundtable) included a workshop to discuss the priorities for advancements in neuroimaging in the diagnostic workup of acute ischemic stroke. The ...
Background— The nucleus tractus solitarius (NTS) is the primary integrative center for baroreflex. Adenosine has been shown to play an important modulatory role in blood pressure control in the NTS.
Dr Forrester’s prediction that resolution of restenosis would require the translational merging of molecular mechanisms of proliferation with local scaffolding and drug-delivery devices appears to ...
Background— B-type natriuretic peptide (BNP), C-reactive protein (CRP), and renin are elevated in persons at risk for cardiovascular disease. However, data that directly compare these markers in the ...
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