By recreating a fetal liver niche, FLOs show how liver and immune cells co-develop. Learn more about new groundbreaking ...

Organoids refer to small-scale organs made up of diverse cell types, exhibiting structures and functions akin to actual organs. Unlike conventional cell cultures, organoids better replicate human ...

Fatty liver disease isn’t just a concern for the overweight—it can strike people of healthy weight and diet, and now scientists think they know why. Two genes previously linked to cancer, RNF43 and ...

As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths. While the treatment options for this aggressive type of cancer remain ...

Scientists identify measurable cellular changes that flag higher cancer risk more than a decade before tumors appear. In A ...

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, ...

Drugs that fail in late stages of development create one of the biggest challenges in global healthcare. In fact, less than 10% of the drugs that move into clinical development survive to approval.

The FDA has qualified AI-Based Histologic Measurement of MASH, or AIM-MASH AI Assist — the first AI drug development tool — ...

Integrated map of scRNA-seq and snRNA-seq data from pig livers at four time points and cellular heterogeneities within each major hepatic cell types. This study is led by Prof. Lusheng Huang (National ...

Acute liver failure is a medical emergency that can cause life threatening complications. It’s most commonly caused by drug overdose in the United States, with acetaminophen being the most common ...