Subjective and objective limitations to exercise and activity are hallmarks of heart failure (HF), regardless of underlying ejection fraction (EF). These limitations relate to cardiovascular ...

Department of Emergency Medicine (Y.-L.L., Y.L., H.T., A.J.E.), University of Nebraska Medical Center, Omaha. Department of Cellular and Integrated Physiology (Y.-L.L ...

Cardiac rehabilitation (CR) can improve cardiovascular health. We identified whether CR participation was associated with fewer subsequent inpatient hospitalizations and emergency department visits ...

Thromboembolic events, including myocardial infarction (MI) or stroke, caused by the rupture or erosion of unstable atherosclerotic plaques are the leading cause of death worldwide. Although most ...

From the Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, Minn (T.J.B., B.J.G.), and J.W. Goethe University, Frankfurt ...

Periodic repolarization dynamics (PRD) is an electrocardiographic biomarker that captures repolarization instability in the low frequency spectrum and is believed to estimate the sympathetic effect on ...

Pretricuspid shunts have been associated with poorer survival rates in patients with Eisenmenger syndrome compared with postricuspid shunts and complex lesions. However, the risk stratification for ...

Epigenetics has transformed our understanding of the molecular basis of complex diseases, including cardiovascular and metabolic disorders. This review offers a comprehensive overview of the current ...

Besides the physiological regulation of water, sodium, and potassium homeostasis, aldosterone modulates several physiological and pathological processes in the cardiovascular system. At the vascular ...

Chronic electronic cigarette (EC) users exhibit a higher susceptibility of LDL (low-density lipoprotein) to undergo oxidation as compared with nonuser controls. However, there is a paucity of data ...

Aortic stenosis is the most common valvular disease requiring valve replacement. Valve replacement therapies have undergone progressive evolution since the 1960s. Over the last 20 years, transcatheter ...

β-Blockers (BBs) are mainstay therapy for heart failure with reduced ejection fraction. However, individual patient responses to BB vary, which may be partially due to genetic variation. The goal of ...