snmjournals.org

Validation of Folate Receptor-α Selectivity of 6 S -5-Methyltetrahydrofolate–Based Radioconjugates: A Prerequisite for Therapeutic Application?

The development of folic acid–based radioconjugates has been proposed for imaging and targeted radionuclide therapy of folate receptor-α (FRα)–positive cancer. Although folic acid binds both the tumor ...
snmjournals.org

Risk Assessment in Large B-Cell Lymphoma Using Metabolic Tumor Volume: Real-World Data from a Multicenter Cohort of Patients Undergoing CAR T-Cell Therapy

Journal of Nuclear Medicine March 2026, jnumed.125.271976; DOI: https://doi.org/10.2967/jnumed.125.271976 ...
snmjournals.org

MIRD Pamphlet No. 21: A Generalized Schema for Radiopharmaceutical Dosimetry—Standardization of Nomenclature

The internal dosimetry schema of the Medical Internal Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine has provided a broad framework for assessment of the absorbed dose to whole ...
snmjournals.org

Posttherapy Radiation Safety Considerations in Radiomicrosphere Treatment with

The radiomicrosphere treatment concept was introduced during the 1960s, and the techniques and clinical applications have been extensively described in the literature (1–5). The delivery of radiation ...
snmjournals.org

Detection of Pulmonary Embolism with Combined Ventilation–Perfusion SPECT and Low-Dose CT: Head-to-Head Comparison with Multidetector CT Angiography

The diagnosis of pulmonary embolism (PE) is usually established by a combination of clinical assessment, D-dimer testing, and imaging with either pulmonary ventilation–perfusion (V/Q) scintigraphy or ...
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Experience with a Simplified, Standardized 4-Hour Gastric-Emptying Protocol

The radionuclide gastric-emptying study has long been the standard method for measuring gastric motility. However, clinicians increasingly express concern about the lack of standardized methodology ...
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Prostate-Specific Membrane Antigen Radioligand Therapy in Patients with Aggressive-Variant Prostate Cancer

Journal of Nuclear Medicine March 2026, jnumed.125.271296; DOI: https://doi.org/10.2967/jnumed.125.271296 ...
snmjournals.org

Assessment of CCR2 PET as a Biomarker for Head and Neck Squamous Cell Carcinoma

Journal of Nuclear Medicine March 2026, jnumed.125.271601; DOI: https://doi.org/10.2967/jnumed.125.271601 ...
snmjournals.org

SPECT Versus PET for [ 177 Lu]Lu-PSMA Response Assessment Using Quantitative RECIP 1.0

Prostate-specific membrane antigen (PSMA) PET/CT is widely used to monitor response during [177Lu]Lu-PSMA radiopharmaceutical therapy (RPT) in metastatic castration-resistant prostate cancer (mCRPC), ...
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Is CXCR4 Theranostics in Oncologic, Cardiovascular, and Inflammatory Diseases Really Happening?

C-X-C motif chemokine receptor 4 (CXCR4) is a transmembrane chemokine receptor involved in various biologic processes, including tumor growth, metastasis, and the homing and retention of hematopoietic ...
snmjournals.org

Enhancement of astatine-211 uptake via the sodium iodide symporter by the addition of ascorbic acid in targeted alpha therapy of thyroid cancer

Journal of Nuclear Medicine February 2019, jnumed.118.222638; DOI: https://doi.org/10.2967/jnumed.118.222638 ...
snmjournals.org

18 F-FDG Avidity in Lymphoma Readdressed: A Study of 766 Patients

PET/CT with 18F-FDG is an important noninvasive diagnostic tool for management of patients with lymphoma, and its use may surpass current guideline recommendations. The aim of the present study is to ...