Eclipsebio's eCOMPASS™ platform integrates AI-optimized RNA design (eNAVIGATE™), in-house prototyping at R&D scale, and deep sequencing-based characterization (eMERGE™) into a single iterative ...

Historically, drug discovery has centred around proteins but as targets become increasing saturated, novel RNA-targeting drugs indicate potential in rare diseases and oncology. Photo by Christoph ...

There are plenty of unanswered questions about the origin of life on Earth. But the research community has largely reached consensus that one of the key steps was the emergence of an RNA molecule that ...

According to the RNA world hypothesis, life began when RNA molecules evolved the ability to make more copies of themselves. Now we have discovered an RNA molecule that is almost capable of this – it ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Codon optimization is a central strategy in recombinant protein production, enabling genes from one organism to be efficiently expressed in another. Conventional methods typically replace ...

A giant impact on the early Earth could have brought the building blocks of RNA to our planet, which new research suggests could have quickly formed in the presence of compounds called borates. When ...

Researchers uncovered a microbe that treats one stop codon as both a termination signal and an amino-acid instruction, revealing surprising genetic flexibility that may inspire new ways to influence ...

Systematic characterization of terminating ribosomes uncovers sequence features influencing ribosome dynamics at stop codons with direct implications in 3' UTR translation.

An illustration of E. coli. Scientists have been racing to shrink the genetic code of this bacterium. Kateryna Kon / Science Photo Library via Getty Images The DNA of nearly all life on Earth is made ...

Liquid culture flasks of bacteria grown in yellow broth covered with tinfoil on a shaker. Bacterial strains needed to be tested every step of the way to create the highly compressed genome. Credit: ...