CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a ...

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

Researchers have used artificial intelligence to design thousands of new DNA switches that can precisely control the expression of a gene in different cell types. Their new approach opens the ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. The research is published in the journal Nature. The ...

First came AlphaFold. Now comes AlphaGenome for DNA. When scientists first sequenced the human genome in 2003, they revealed the full set of DNA instructions that make a person. But we still didn’t ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA knots that behave less like static quirks and more like hidden switches.

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...